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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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BAY 80-6946 (Copanlisib CAS number 1032568-63-0) is a small molecule inhibitor targeting class I phosphatidylinositol-3-kinase (PI3K) with potent inhibitory activity against PI3K- and PI3K- isoforms By blocking PI3K enzymatic activity Copanlisib interferes with downstream signaling pathways crucial for cell proliferation and survival In vitro studies demonstrate notable antiproliferative effects in cancer cell lines such as HuCCT-1 and EGI-1 (KRASG12D mutants) exhibiting IC50 values of approximately 147 nM and 137 nM respectively Clinical trials indicate potential utility in treating B-cell malignancies like chronic lymphocytic leukemia and non-Hodgkin lymphoma
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CO23 is a selective thyroid hormone receptor (TR) α agonist for research applications. It is an off-white to light-yellow solid with reported ability to cross the blood-brain barrier and is used to study growth and developmental regulation mediated by TRα. The compound is provided with defined purity and storage recommendations for stable handling.
Selective thyroid hormone receptor (TRα) agonist.
Reported to cross the blood-brain barrier.
Off-white to light-yellow solid appearance.
Purity 98.0% as supplied.
Available as solid and as a 10 mM solution in DMSO.
Storage recommended at -20°C for powder and -80°C in solvent for long term.
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3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a deaminated sialic acid derivative provided as a white to off-white solid for biochemical research. The compound offers high purity and reliable aqueous solubility for studies in glycobiology, sialylation, and related analytical workflows.
High purity (99.9%) suitable for analytical and biochemical applications.
Water soluble at up to 100 mg/mL; ultrasonic assistance may be required.
Solid form with defined storage stability under recommended conditions.
Molecular weight 268.22 g/mol and formula C9H16O9 for precise mass calculations.
Relevant endogenous metabolite for studies of sialic acid biology.
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CO23 is a selective thyroid hormone receptor alpha (TRα) agonist used in research to study growth, development, and thyroid signaling. It has been reported to cross the blood-brain barrier and is supplied as a high-purity research chemical for in vitro and in vivo studies.
Selective TRα agonist for targeted thyroid receptor modulation.
Demonstrated blood-brain barrier penetration.
High purity (98.0%) for reliable experimental results.
Soluble in DMSO at 250 mg/mL; ultrasonic assistance recommended.
Solid, off-white to light yellow appearance; powder stable at -20 °C.
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Ascorbate oxidase is a homodimeric enzyme which comprises 552 amino acid residues per subunit (zucchini). It corresponds to a molecular mass of 70kDa per subunit. This enzyme is mainly found in plants fungi and eubacteria.
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